What next when metformin isn't enough for type 2 diabetes?
نویسندگان
چکیده
This patient-centered case vignette offers insight into how best to choose among additional oral agents, basal insulin, or the newer GLP-1 receptor agonists.
منابع مشابه
Thiazolidinediones versus metformin on improving abnormal liver enzymes in patients with type 2 diabetes mellitus: a meta-analysis
Background Liver enzyme abnormalities are common in patients with type 2 diabetes. Currently, the inverse relationship between elevated liver enzymes and antidiabetics intake may be explained by rigorous treatment and good control. However, few studies have directly explored the influence of antidiabetics on abnormal liver function, especially the comparison between two insulin sensitizers-thia...
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Type 2 diabetes mellitus is a worldwide epidemic disorder with considerable health and economic consequences. Metformin is one of the most commonly prescribed oral antidiabetic drugs. Pharmacogenetic studies showed that variants in genes related to the pharmacokinetics of metformin were associated with glucose-lowering effect of metformin. The aim of this study was to evaluate pharmacogenetic v...
متن کاملShould physicians prescribe metformin to women with polycystic ovary syndrome PCOS?
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متن کاملاثر متفورمین در کنترل قند خون بیماران دیابتی نوع دوم تحت درمان با انسولین
Background: Patients with type 2 diabetes are often obese and require large dose of insulin to achieve glycemic control. Insulin therapy often cause weight gain and results in increasing insulin requirements. This study was conducted to evaluate the efficacy of metformin in combination with insulin in patients with type 2 diabetes poorly controlled with insulin therapy alone. Materials and Meth...
متن کاملContinuation of metformin after introduction of insulin in type 2 diabetes.
Metformin is the cornerstone of treatment early in the course of type 2 diabetes. Recent studies also provide evidence for the benefits of metformin when given late in the course of the disease, after the introduction of insulin.1 2 However, because metformin targets insulin resistance in overweight patients, can it be as beneficial in non-obese patients? In the linked randomised controlled tri...
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عنوان ژورنال:
- The Journal of family practice
دوره 65 2 شماره
صفحات -
تاریخ انتشار 2016